DENTAL IMPLANTATSIYADA SUYAK REGENERATSIYASINI TEZLASHTIRISHDA PRF (PLATELET RICH FIBRIN) QO‘LLANILISHINING SAMARADORLIGI
Keywords:
PRF, dental implantatsiya, suyak regeneratsiyasi, fibrin, o‘sish omillari, osteointegratsiya, biomateriallar.Abstract
Ushbu maqolada dental implantatsiya jarayonida suyak to‘qimalarining regeneratsiyasini tezlashtirishda PRF (Platelet Rich Fibrin) texnologiyasining o‘rni va samaradorligi yoritilgan. PRF – bu bemorning o‘z qonidan olinadigan tabiiy biomaterial bo‘lib, unda o‘sish omillari va fibrin tolalari mavjud. Ushbu modda implant atrofidagi suyak va yumshoq to‘qimalarning tez tiklanishiga, yallig‘lanishning kamayishiga hamda implantning suyak bilan integratsiyasiga yordam beradi. Maqolada PRFning ishlash mexanizmi, klinik amaliyotdagi afzalliklari va natijadorligi bo‘yicha ilmiy adabiyotlar tahlil qilingan.
References
1. Choukroun, J., Adda, F., Schoeffler, C., & Vervelle, A. (2001). PRF: An opportunity in perio-implantology. Implantodontie, 42(3), 141–152.
2.Dohan, D. M., Choukroun, J., Diss, A., Dohan, S. L., Dohan, A. J. J., & Mouhyi, J. (2006). Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 101(3), e37–e44.
3. Simonpieri, A., Del Corso, M., Sammartino, G., & Dohan Ehrenfest, D. M. (2009). The relevance of Choukroun’s PRF and metronidazole during complex maxillary rehabilitations using bone allograft. Implant Dentistry, 18(1), 82–91.
4. Dohan Ehrenfest, D. M., Del Corso, M., Diss, A., Mouhyi, J., & Charrier, J. B. (2010). Three-dimensional architecture and cell composition of a Choukroun’s platelet-rich fibrin clot and membrane. Journal of Periodontology, 81(4), 546–555.
5. Toffler, M. (2012). Guided bone regeneration (GBR) using platelet-rich fibrin (PRF) and particulate bone grafts. Practical Procedures & Aesthetic Dentistry, 24(3), 123–129.
6. Del Corso, M., Sammartino, G., & Dohan Ehrenfest, D. M. (2014). Relevance of the slow speed centrifugation concept for PRF-based matrices. European Journal of Dentistry, 8(4), 96–102.
7. Abdurahmonov, Sh. (2019). Dental implantatsiyada regeneratsion biomateriallarning klinik samaradorligi. Toshkent: Tibbiyot nashriyoti. 40–48 bet.
8. Kurbanov, U. R., Ismoilova, D. A., & Tursunova, Z. M. (2021). PRF texnologiyasining suyak regeneratsiyasidagi o‘rni. Samarqand: SamDTI Ilmiy axborot to‘plami, 73–78 bet.
9. Qosimov, A. S. (2020). Dental implantlarning osteointegratsiyasi jarayonida PRFning ahamiyati. Andijon tibbiyot instituti ilmiy maqolalar to‘plami, 101–106 bet.
10. Rasulov, B. M. (2020). Stomatologiyada biomateriallar va regeneratsion texnologiyalar. Toshkent: Innovatsiya nashriyoti, 56–65 bet.
11. Toshkent Tibbiyot Akademiyasi. (2021). PRF qo‘llashning klinik natijalari bo‘yicha hisobot. Toshkent: TTA Stomatologiya kafedrasi nashri, 31–34 bet.
12. O‘zbekiston Respublikasi Stomatologlar Assotsiatsiyasi. (2022). Stomatologiyada zamonaviy regeneratsion yondashuvlar: klinik tahlillar to‘plami. Toshkent: O‘RSA nashriyoti, 17–21 bet.
